Theophylline

Theophylline is a drug, a PDE inhibitor, that is widely used in pharmacotherapy.

Chemical formulas of the drug are :

• 3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione
• 1,3-dimethylxanthine
• and C7H8N4O2

It has molecular weight of 180.16.

The main actions of theophylline are :

• relaxation of bronchial smooth muscle[?]
• positive inotropic effect
• positive chronotropic effect
• lowers blood pressure
• increases renal blood flow
• some anti-inflammatory effect

The main therapeutic uses of theophylline are :

• chronic obstructive diseases of the airways
  • COPD
  • bronchial asthma